- Jorge Martin (kontrak multi-tahunan)
- Kandidat rider kedua: Marco Bezzecchi dan Fabio Di Giannantonio

Ducati Lenovo Team (Ducati)

- Pecco Bagnaia (2026)
- Marc Marquez

Monster Energy Yamaha (Yamaha)

- Fabio Quartararo (2026)
- Kandidat rider kedua: Alex Rins

Red Bull KTM Factory Racing (KTM)

- Pedro Acosta (multi-tahunan)
- Brad Binder (2026)

Repsol Honda (Honda)

- Luca Marini (2025)
- Kandidat rider kedua: Joan Mir, Jack Miller

Red Bull GASGAS Tech 3 (KTM)

- Enea Bastianini
- Maverick Vinales

LCR Honda Idemitsu-Castrol (Honda)

- Johann Zarco (2025)
- Kandidat rider kedua: Takaaki Nakagami, Ai Ogura

Trackhouse Racing (Aprilia)

Kandidat: Joe Roberts, Raul Fernandez, Joan Mir, Miguel Oliveira